Based on Bonnie Garmus’ best-selling debut novel, Lessons in Chemistry, set in the early 1950s, follows Elizabeth Zott (Larson), whose dream of being a scientist is put on hold in a patriarchal society. When Elizabeth finds herself fired from her lab, she accepts a job as a host on a TV cooking show, and sets out to teach a nation of overlooked housewives – and the men who are suddenly listening – a lot more than recipes.